From my time in clinical PET, I've noticed a variation in the calculations of Standard Update Values (SUV) between different manufacturers software platforms. I'm not sure why this occurs and perhaps it could be down to the use of different calculation algorithms being utilised.
Practitioners, physicists and consultants need to be aware however of the potential for variations in SUV calculations between different manufacturers. It would be interesting to conduct a validated comparison project between different vendors software to assess the potential variations in calculations. This also highlights to me the need of ensuring practitioners have a strong understanding of quantification within nuclear medicine and in particular hybrid practice. Ensuring the skills, training and education frameworks are in place is integral to the future of effective / innovative service provision.